Methiothepin maleate ( Methiothepin Maleate | Metitepine | HCVIN281816 )

产品货号. M18192 CAS No. 19728-88-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Methiothepin maleate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Methiothepin 是一种 5-HT1、5-HT6、5-HT7 血清素受体拮抗剂，可阻断血清素自身受体。
产品描述

Methiothepin Maleate is an inhibitor of HCV infection and cell-to-cell transmission that acts by targeting the HCV E2 glycoprotein.
体外实验

Methiothepin maleate is a 5-HT receptor antagonist, with pKds of 7.10, 7.28, 7.56, and 6.99 for 5-HT1A, 5HT1B, 5HT1C, 5HT1D. Methiothepin mesylate also shows pKds of 7.0, 7.8, 8.74, and 8.99 for 5-HT5A, 5-HT5B, 5-HT6, and 5-HT7, respectively. Methiothepin exhibits high affinity at 5-HT2A, 5HT2B, and 5HT2C with pKis of 8.50, 8.68, and 8.35, respectively.
体内实验

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同义词

Methiothepin Maleate | Metitepine | HCVIN281816
通路

Others
靶点

Other Targets
受体

5-HT1|5-HT6|5-HT7
研究领域

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适应症

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CAS Number

19728-88-2
分子量

472.62
分子式

C24H28N2O4S2
纯度

>98% (HPLC)
溶解度

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SMILES

CN1CCN(CC1)C2CC3=CC=CC=C3SC4=C2C=C(C=C4)SC.C(=CC(=O)O)C(=O)O
化学全称

1-Methyl-4-(3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine Maleate